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All Publications by Markus G. Manz


PubM​​​​ed​​​​​​


Latest Publications - Dr. Jane Doe

Selected Publications - Hematopoiesis

Clonal dynamics after allogeneic haematopoietic cell transplantation
Nature
Oct 2024
Aging drives Tet2+/- clonal hematopoiesis via IL-1 signaling
Blood
Feb 2023
IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice
Blood
Jan 2022
Clonal hematopoiesis in donors and long-term survivors of related allogeneic hematopoietic stem cell transplantation
Blood
Apr 2020
Pathogen-Induced TLR4-TRIF Innate Immune Signaling in Hematopoietic Stem Cells Promotes Proliferation but Reduces Competitive Fitness
Cell Stem Cell
Jul 2017
Enhanced thrombopoietin but not G-CSF receptor stimulation induces self-renewing hematopoietic stem cell divisions in vivo
Blood
Jun 2016
Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis
Blood
Aug 2014
Development and function of human innate immune cells in a humanized mouse model
Nature Biotechnology
Apr 2014
Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation
Journal of Experimental Medicine
Feb 2011


Latest Publications - Dr. Jane Doe

Selected Publications - Haematologic Malignancies

Single-cell landscape of innate and acquired drug resistance in acute myeloid leukemia
Nature Communications
Oct 2024
Ex vivo drug response heterogeneity reveals personalized therapeutic strategies for patients with multiple myeloma
Nature Cancer
May 2023
MPL expression on AML blasts predicts peripheral blood neutropenia and thrombocytopenia
Blood
Nov 2016
inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice
Blood
Nov 2016


Latest Publications - Dr. Jane Doe

Selected Publications - Immunotherapies

A single-chain variable fragment-based bispecific T-cell activating antibody against CD117 enables T-cell mediated lysis of acute myeloid leukemia and hematopoietic stem and progenitor cells
Hemasphere
Nov 2024
Efficient combinatorial adaptor-mediated targeting of acute myeloid leukemia with CAR T-cells
Leukemia
Sep 2024
Targeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells
EMBO Molecular Medicine
Mar 2024
Anti-CD117 CAR T cells incorporating a safety switch eradicate human acute myeloid leukemia and hematopoietic stem cells
Molecular Therapy Oncolytics
Jul 2023
Impact of Ligand Size and Conjugation Chemistry on the Performance of Universal Chimeric Antigen Receptor T-Cells for Tumor Killing
Bioconjugate Chemistry
Jul 2020
Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells
Leukemia
Oct 2020


Latest Publications - Dr. Jane Doe

Selected Reviews and Commentaries

Precision pre-HSCT conditioning by targeting cMPL
Blood
Jun 2025
Gut microbiota fuels clonal hematopoiesis
Cell Research
Jun 2025
IL-1 in aging and pathologies of hematopoietic stem cells
Blood
Jul 2024
Twisted: Escape of epitope-edited healthy cells from immune attack
Journal of Experimental Medicine
Dec 2024
TLR1/2-stimulated DCs "prime" HSCs via IL-1β
Blood
Oct 2022
Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection
Journal of Experimental Medicine
Jul 2021
Anti-CD117 immunotherapy to eliminate hematopoietic and leukemia stem cells
Experimental Hematology
Jan 2021
Clonal hematopoiesis in hematopoietic stem cell transplantation
Current Opinion on Hematology
Mar 2021
Selective CD117+ HSC exchange therapy
Blood
May 2019
Quantification and three-dimensional microanatomical organization of the bone marrow
Blood Advances
Feb 2017
Emergency granulopoiesis
Nature Reviews Immunology
May 2014
Human hemato-lymphoid system mice: current use and future potential for medicine
Annual Review of Immunology
Jan 2013